Reaction Details Report a problem with these data
Target
D1 dopamine receptor
Ligand
BDBM50049047
Substrate
n/a
Ki
20.2±n/a nM
Comments
PDSP_664
Citation
 Salmi, P; Isacson, R; Kull, B Dihydrexidine--the first full dopamine D1 receptor agonist. CNS Drug Rev 10:230-42 (2004) [PubMed]  Article 
Target
Name:
D1 dopamine receptor
Synonyms:
D1 dopamine receptor | DOPAMINE D1 | DRD1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
8818.33
Organism:
Monkey
Description:
Q5I6B7
Residue:
78
Sequence:
VIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPA
  
Inhibitor
Name:
BDBM50049047
Synonyms:
5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | CHEMBL101446 | Dihydrexidine | Dihydrexidine, DHX
Type:
Small organic molecule
Emp. Form.:
C17H17NO2
Mol. Mass.:
267.3224
SMILES:
Oc1cc2CCC3NCc4ccccc4C3c2cc1O
Structure:
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