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Target
Phospholipase D1
Ligand
BDBM87129
Substrate
n/a
Meas. Tech.
Cellular PLD1 concentration response
IC50
28±n/a nM
Citation
 PubChem, PC Cellular PLD1 concentration response PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase D1
Synonyms:
Choline phosphatase 1 | PLD 1 | PLD1 | PLD1_HUMAN | Phosphatidylcholine-hydrolyzing phospholipase D1 | Phospholipase D (PLD) | Phospholipase D1 | Phospholipase D1 (PLD1) | Phospholipase D2 (PLD2) | hPLD1
Type:
Protein
Mol. Mass.:
124219.92
Organism:
Homo sapiens (Human)
Description:
Q13393
Residue:
1074
Sequence:
MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSAIYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNCCGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRIDNLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKGYFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGLKPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
  
Inhibitor
Name:
BDBM87129
Synonyms:
N-[(1S)-2-[4-(5-iodo-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-2-naphthamide;2,2,2-trifluoroacetic acid | N-[(2S)-1-[4-(5-iodanyl-2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]naphthalene-2-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid | N-[(2S)-1-[4-(5-iodo-2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]propan-2-yl]-2-naphthalenecarboxamide;2,2,2-trifluoroacetic acid | N-[(2S)-1-[4-(5-iodo-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]naphthalene-2-carboxamide;2,2,2-trifluoroacetic acid | VU0409797-1 | cid_53469893
Type:
Small organic molecule
Emp. Form.:
C26H27IN4O2
Mol. Mass.:
554.4227
SMILES:
C[C@@H](CN1CCC(CC1)n1c2ccc(I)cc2[nH]c1=O)NC(=O)c1ccc2ccccc2c1
Structure:
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