Reaction Details Report a problem with these data
Target
V-type proton ATPase subunit c'
Ligand
BDBM87568
Substrate
n/a
Meas. Tech.
Dose Response of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin, Cherry Pick 2
EC50
7257±n/a nM
Citation
 PubChem, PC Dose Response of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin, Cherry Pick 2 PubChem Bioassay (2012)[AID] 
Target
Name:
V-type proton ATPase subunit c'
Synonyms:
CLS9 | TFP3 | VATL2_YEAST | VMA11 | Vma11p
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17039.28
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_6325022
Residue:
164
Sequence:
MSTQLASNIYAPLYAPFFGFAGCAAAMVLSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGMVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTRGSE
  
Inhibitor
Name:
BDBM87568
Synonyms:
5-[(7-fluoranyl-9H-fluoren-2-yl)imino]furan-2-one | 5-[(7-fluoro-9H-fluoren-2-yl)imino]-2-furanone | 5-[(7-fluoro-9H-fluoren-2-yl)imino]furan-2-one | MLS002667319 | SMR001557087 | cid_241922
Type:
Small organic molecule
Emp. Form.:
C17H10FNO2
Mol. Mass.:
279.2652
SMILES:
Fc1ccc-2c(Cc3cc(ccc-23)\N=C2/OC(=O)C=C2)c1 |c:20|
Structure:
Search PDB for entries with ligand similarity: