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Target
Melanocortin receptor 4
Ligand
BDBM88581
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64622±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88581
Synonyms:
1-(2,1,3-benzoxadiazol-4-ylsulfonyl)-N-(6-ethoxy-1,3-benzothiazol-2-yl)-3-piperidinecarboxamide | 1-(2,1,3-benzoxadiazol-4-ylsulfonyl)-N-(6-ethoxy-1,3-benzothiazol-2-yl)piperidine-3-carboxamide | 1-benzofurazan-4-ylsulfonyl-N-(6-ethoxy-1,3-benzothiazol-2-yl)nipecotamide | MLS000521743 | SMR000132151 | cid_9550171
Type:
Small organic molecule
Emp. Form.:
C21H21N5O5S2
Mol. Mass.:
487.552
SMILES:
CCOc1ccc2nc(NC(=O)C3CCCN(C3)S(=O)(=O)c3cccc4nonc34)sc2c1
Structure:
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