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Target
Melanocortin receptor 4
Ligand
BDBM88606
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64577±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88606
Synonyms:
3-(1,3-diketo-4-nitro-isoindolin-2-yl)propionic acid [2-[4-(N-isopropylanilino)anilino]-2-keto-ethyl] ester | 3-(4-nitro-1,3-dioxo-2-isoindolyl)propanoic acid [2-oxo-2-[4-(N-propan-2-ylanilino)anilino]ethyl] ester | MLS000375182 | SMR000254435 | [2-oxidanylidene-2-[[4-[phenyl(propan-2-yl)amino]phenyl]amino]ethyl] 3-[4-nitro-1,3-bis(oxidanylidene)isoindol-2-yl]propanoate | [2-oxo-2-[4-(N-propan-2-ylanilino)anilino]ethyl] 3-(4-nitro-1,3-dioxoisoindol-2-yl)propanoate | cid_2370680
Type:
Small organic molecule
Emp. Form.:
C28H26N4O7
Mol. Mass.:
530.5286
SMILES:
CC(C)N(c1ccccc1)c1ccc(NC(=O)COC(=O)CCN2C(=O)c3cccc(c3C2=O)[N+]([O-])=O)cc1
Structure:
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