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Target
Melanocortin receptor 4
Ligand
BDBM88628
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64574±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88628
Synonyms:
2-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)sulfanyl]-N-(2-morpholin-4-ylethyl)ethanamide | 2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)sulfanyl]-N-(2-morpholin-4-ylethyl)acetamide | 2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)thio]-N-(2-morpholin-4-ylethyl)acetamide | 2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)thio]-N-(2-morpholinoethyl)acetamide | 2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)thio]-N-[2-(4-morpholinyl)ethyl]acetamide | MLS000731356 | SMR000309631 | cid_16193930
Type:
Small organic molecule
Emp. Form.:
C21H26ClN3O2S
Mol. Mass.:
419.968
SMILES:
Clc1ccc2c(SCC(=O)NCCN3CCOCC3)c3CCCCc3nc2c1
Structure:
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