Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89067
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen.
IC50
35330±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89067
Synonyms:
4-chlorobenzoic acid [(Z)-[amino-(3-cyclopentyloxy-4-methoxyphenyl)methylidene]amino] ester | 4-chlorobenzoic acid [(Z)-[amino-[3-(cyclopentoxy)-4-methoxy-phenyl]methylene]amino] ester | MLS-0454736.0001 | [(Z)-[amino-(3-cyclopentyloxy-4-methoxyphenyl)methylidene]amino] 4-chlorobenzoate | [(Z)-[azanyl-(3-cyclopentyloxy-4-methoxy-phenyl)methylidene]amino] 4-chloranylbenzoate | cid_9584546
Type:
Small organic molecule
Emp. Form.:
C20H21ClN2O4
Mol. Mass.:
388.845
SMILES:
COc1ccc(cc1OC1CCCC1)C(=N)NOC(=O)c1ccc(Cl)cc1
Structure:
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