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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90226
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90226
Synonyms:
4-(2-furoylamino)benzoic acid phenyl ester | 4-[[2-furanyl(oxo)methyl]amino]benzoic acid phenyl ester | MLS000665169 | SMR000270393 | cid_1121535 | phenyl 4-(2-furoylamino)benzoate | phenyl 4-(furan-2-carbonylamino)benzoate | phenyl 4-(furan-2-ylcarbonylamino)benzoate
Type:
Small organic molecule
Emp. Form.:
C18H13NO4
Mol. Mass.:
307.3001
SMILES:
O=C(Nc1ccc(cc1)C(=O)Oc1ccccc1)c1ccco1
Structure:
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