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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90227
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90227
Synonyms:
MLS000665344 | N-(4-methyl-1,3-thiazol-2-yl)-2-(2-nitrophenyl)acetamide | N-(4-methyl-1,3-thiazol-2-yl)-2-(2-nitrophenyl)ethanamide | N-(4-methyl-2-thiazolyl)-2-(2-nitrophenyl)acetamide | N-(4-methylthiazol-2-yl)-2-(2-nitrophenyl)acetamide | SMR000270444 | cid_1122080
Type:
Small organic molecule
Emp. Form.:
C12H11N3O3S
Mol. Mass.:
277.299
SMILES:
Cc1csc(NC(=O)Cc2ccccc2[N+]([O-])=O)n1
Structure:
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