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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM88884
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
7400±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM88884
Synonyms:
(E)-3-(4-aminophenyl)-1-(2-furanyl)-2-propen-1-one | (E)-3-(4-aminophenyl)-1-(2-furyl)prop-2-en-1-one | (E)-3-(4-aminophenyl)-1-(furan-2-yl)prop-2-en-1-one | 3-(4-aminophenyl)-1-(2-furyl)-2-propen-1-one | MLS000665413 | SMR000270648 | cid_5734124
Type:
Small organic molecule
Emp. Form.:
C13H11NO2
Mol. Mass.:
213.2319
SMILES:
Nc1ccc(\C=C\C(=O)c2ccco2)cc1
Structure:
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