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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90238
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90238
Synonyms:
MLS000391896 | N-[(E)-(3-nitrophenyl)methylideneamino]-3,4,5,6-tetrahydro-2H-azepin-7-amine | SMR000260929 | [(E)-(3-nitrobenzylidene)amino]-(3,4,5,6-tetrahydro-2H-azepin-7-yl)amine | cid_9710601
Type:
Small organic molecule
Emp. Form.:
C13H16N4O2
Mol. Mass.:
260.2917
SMILES:
[O-][N+](=O)c1cccc([CH+][N-]NC2=NCCCCC2)c1 |t:11|
Structure:
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