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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM46952
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
13700±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM46952
Synonyms:
4-chloranyl-N-(2-morpholin-4-ylcyclohexyl)benzenesulfonamide | 4-chloro-N-(2-morpholin-4-ylcyclohexyl)benzenesulfonamide | 4-chloro-N-(2-morpholinocyclohexyl)benzenesulfonamide | 4-chloro-N-[2-(4-morpholinyl)cyclohexyl]benzenesulfonamide | MLS000713637 | SMR000273118 | cid_2911646
Type:
Small organic molecule
Emp. Form.:
C16H23ClN2O3S
Mol. Mass.:
358.883
SMILES:
Clc1ccc(cc1)S(=O)(=O)NC1CCCCC1N1CCOCC1
Structure:
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