Reaction Details Report a problem with these data
Target
dCTP deaminase
Ligand
BDBM91592
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
8±0
Temperature
298.15±0 K
Ki
5.47e+5±n/a nM
Citation
 Musso-Buendía, JA; Vidal, AE; Kasinthan, G; Nguyen, C; Carrero-Lérida, J; Ruiz-Pérez, LM; Wilson, K; Johansson, NG; Gilbert, IH; González-Pacanowska, D Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Campylobacter jejuni. J Enzyme Inhib Med Chem 24:111-6 (2009) [PubMed]  Article 
Target
Name:
dCTP deaminase
Synonyms:
DCD_CAMJE | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) | dcd
Type:
Protein
Mol. Mass.:
20698.65
Organism:
Campylobacter jejuni
Description:
n/a
Residue:
186
Sequence:
MGLKADNWIRKMALEHKMIEPFCEANIGKGVVSYGLSSYGYDIRVGREFKIFTNVNSTVVDPKNFVEENVVDFEGDVCIVPANSFALARTIEYFKMPDNVLAICLGKSTYARCGIIVNVTPFEPGFEGHITIEISNTTPLPAKIYANEGIAQVLFLQGDEKCDTTYKDKKGKYQAQTGITLPRILK
  
Inhibitor
Name:
BDBM91592
Synonyms:
dUTPase inhibitor, 3
Type:
Small organic molecule
Emp. Form.:
C20H24N2O5
Mol. Mass.:
372.415
SMILES:
O=C(OCC1OC(C=C1)n1ccc(=O)[nH]c1=O)C12CC3CC(CC(C3)C1)C2 |c:7,TLB:20:21:19.24.18:25,24:19:26:23.25.22,24:23:26:20.19.18,THB:20:19:25:26.21.22|
Structure:
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