Reaction Details Report a problem with these data
Target
dCTP deaminase
Ligand
BDBM50173554
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
8±0
Temperature
298.15±0 K
Ki
1.000000e+9±n/a nM
Citation
 Musso-Buendía, JA; Vidal, AE; Kasinthan, G; Nguyen, C; Carrero-Lérida, J; Ruiz-Pérez, LM; Wilson, K; Johansson, NG; Gilbert, IH; González-Pacanowska, D Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Campylobacter jejuni. J Enzyme Inhib Med Chem 24:111-6 (2009) [PubMed]  Article 
Target
Name:
dCTP deaminase
Synonyms:
DCD_CAMJE | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) | dcd
Type:
Protein
Mol. Mass.:
20698.65
Organism:
Campylobacter jejuni
Description:
n/a
Residue:
186
Sequence:
MGLKADNWIRKMALEHKMIEPFCEANIGKGVVSYGLSSYGYDIRVGREFKIFTNVNSTVVDPKNFVEENVVDFEGDVCIVPANSFALARTIEYFKMPDNVLAICLGKSTYARCGIIVNVTPFEPGFEGHITIEISNTTPLPAKIYANEGIAQVLFLQGDEKCDTTYKDKKGKYQAQTGITLPRILK
  
Inhibitor
Name:
BDBM50173554
Synonyms:
CHEMBL194480 | Hexadecanoic acid 5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl ester | dUTPase inhibitor, 4
Type:
Small organic molecule
Emp. Form.:
C25H40N2O5
Mol. Mass.:
448.5955
SMILES:
CCCCCCCCCCCCCCCC(=O)OCC1OC(C=C1)n1ccc(=O)[nH]c1=O |c:22|
Structure:
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