Reaction Details Report a problem with these data
Target
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Ligand
BDBM92538
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
4.0e+4±n/a nM
Citation
 Dupouy, C; Zhang, C; Padilla, A; Pochet, S; Kaminski, PA Probing the active site of the deoxynucleotide N-hydrolase Rcl encoded by the rat gene c6orf108. J Biol Chem 285:41806-14 (2010) [PubMed]  Article 
Target
Name:
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Synonyms:
DNPH1_RAT | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) D69N | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) E93Q | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) S117A | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) Y13F | Dnph1 | Rcl | c-Myc-responsive protein Rcl
Type:
Enzyme
Mol. Mass.:
17775.23
Organism:
Rattus norvegicus (Rat)
Description:
O35820
Residue:
163
Sequence:
MAASGEQAPCSVYFCGSIRGGREDQALYARIVSRLRRYGKVLTEHVADAELEPLGEEAAGGDQFIHEQDLNWLQQADVVVAEVTQPSLGVGYELGRAVALGKPILCLFRPQSGRVLSAMIRGAADGSRFQVWDYAEGEVETMLDRYFEAYLPQKTASSSHPSA
  
Inhibitor
Name:
BDBM92538
Synonyms:
AMP | [5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate | adenosine 5'-phosphate group
Type:
Small molecule
Emp. Form.:
C10H12N5O7P
Mol. Mass.:
345.2064
SMILES:
Nc1ncnc2n(cnc12)C1OC(COP([O-])([O-])=O)C(O)C1O
Structure:
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