Target
Stromal cell-derived factor 1
Ligand
BDBM86004
Substrate
n/a
Meas. Tech.
Tryptophan Fluorescence Assay
Temperature
293.15±0 K
IC50
1.5e+4± 3e+3 nM
Citation
 Hachet-Haas, MBalabanian, KRohmer, FPons, FFranchet, CLecat, SChow, KYDagher, RGizzi, PDidier, BLagane, BKellenberger, EBonnet, DBaleux, FHaiech, JParmentier, MFrossard, NArenzana-Seisdedos, FHibert, MGalzi, JL Small neutralizing molecules to inhibit actions of the chemokine CXCL12. J Biol Chem 283:23189-99 (2008) [PubMed]  Article 
Target
Name:
Stromal cell-derived factor 1
Synonyms:
CXCL12 | Chemokine CXCL12 | SDF1 | SDF1A | SDF1B | SDF1_HUMAN
Type:
Enzyme
Mol. Mass.:
10677.83
Organism:
Homo sapiens (Human)
Description:
P48061
Residue:
93
Sequence:
MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM
  
Inhibitor
Name:
BDBM86004
Synonyms:
Chalcone 2 | Chalcone, 3
Type:
Small organic molecule
Emp. Form.:
C15H12O2
Mol. Mass.:
224.2546
SMILES:
Oc1ccc(\C=C\C(=O)c2ccccc2)cc1
Structure:
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