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Target
Receptor-interacting serine/threonine-protein kinase 2
Ligand
BDBM54724
Substrate
n/a
IC50
1684±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Receptor-interacting serine/threonine-protein kinase 2
Synonyms:
CARDIAK | RICK | RIP2 | RIPK2 | RIPK2_HUMAN | Serine/threonine-protein kinase RIPK2 | Tyrosine-protein kinase RIPK2 | receptor-interacting serine/threonine-protein kinase 2
Type:
Protein
Mol. Mass.:
61201.30
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
540
Sequence:
MNGEAICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSSKSAPEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLKKTKLQSVSSAIHLCDKKKMELSLNIPVNHGPQEESCGSSQLHENSGSPETSRSLPAPQDNDFLSRKAQDCYFMKLHHCPGNHSWDSTISGSQRAAFCDHKTTPCSSAIINPLSTAGNSERLQPGIAQQWIQSKREDIVNQMTEACLNQSLDALLSRDLIMKEDYELVSTKPTRTSKVRQLLDTTDIQGEEFAKVIVQKLKDNKQMGLQPYPEILVVSRSPSLNLLQNKSM
  
Inhibitor
Name:
BDBM54724
Synonyms:
1-anilino-3-phenyl-1H-pyrrole-2,5-dione | 1-anilino-3-phenyl-3-pyrroline-2,5-quinone | 1-anilino-3-phenylpyrrole-2,5-dione | 3-phenyl-1-phenylazanyl-pyrrole-2,5-dione | MLS000540410 | SMR000125668 | cid_1484338
Type:
Small organic molecule
Emp. Form.:
C16H12N2O2
Mol. Mass.:
264.2787
SMILES:
O=C1C=C(C(=O)N1Nc1ccccc1)c1ccccc1 |c:2|
Structure:
Search PDB for entries with ligand similarity: