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Target
Sentrin-specific protease 8
Ligand
BDBM93629
Substrate
n/a
IC50
35300±4910 nM
Citation
 PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay (2012)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM93629
Synonyms:
Isonicotinic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide | MLS000768056 | N-[(E)-(5-nitro-2-furanyl)methylideneamino]-4-pyridinecarboxamide | N-[(E)-(5-nitro-2-furyl)methyleneamino]isonicotinamide | N-[(E)-(5-nitrofuran-2-yl)methylideneamino]pyridine-4-carboxamide | SMR000431365 | cid_5469569
Type:
Small organic molecule
Emp. Form.:
C11H8N4O4
Mol. Mass.:
260.2056
SMILES:
[O-][N+](=O)c1ccc(\C=N\NC(=O)c2ccncc2)o1
Structure:
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