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Target
Sentrin-specific protease 8
Ligand
BDBM93674
Substrate
n/a
IC50
>100000±0 nM
Citation
 PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay (2012)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM93674
Synonyms:
(E)-(2-methylbenzimidazol-1-yl)-[(5-nitro-2-furyl)methylene]amine | (E)-N-(2-methyl-1-benzimidazolyl)-1-(5-nitro-2-furanyl)methanimine | (E)-N-(2-methylbenzimidazol-1-yl)-1-(5-nitrofuran-2-yl)methanimine | 2-methyl-N-[(5-nitro-2-furyl)methylene]-1H-benzimidazol-1-amine | MLS000578078 | SMR000186288 | cid_9563275
Type:
Small organic molecule
Emp. Form.:
C13H10N4O3
Mol. Mass.:
270.2435
SMILES:
Cc1nc2ccccc2n1\N=C\c1ccc(o1)[N+]([O-])=O
Structure:
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