Reaction Details
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Report a problem with these dataTarget
Protein skinhead-1
Ligand
BDBM93724
Substrate
n/a
IC50
2540±n/a nM
Citation
PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
Inhibitor
Name:
BDBM93724
Synonyms:
5-(5-bromanylfuran-2-yl)-3-phenyl-1,2,4-oxadiazole | 5-(5-bromo-2-furanyl)-3-phenyl-1,2,4-oxadiazole | 5-(5-bromo-2-furyl)-3-phenyl-1,2,4-oxadiazole | 5-(5-bromofuran-2-yl)-3-phenyl-1,2,4-oxadiazole | MLS000063153 | SMR000072090 | cid_752705
Type:
Small organic molecule
Emp. Form.:
C12H7BrN2O2
Mol. Mass.:
291.1
SMILES:
Brc1ccc(o1)-c1nc(no1)-c1ccccc1
Structure:
