Reaction Details
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Report a problem with these dataTarget
Protein skinhead-1
Ligand
BDBM37971
Substrate
n/a
IC50
21900±n/a nM
Citation
PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
Inhibitor
Name:
BDBM37971
Synonyms:
7-Oxo-7H-thiazolo[3,2-a]pyrimidine-5-carboxylic acid methyl ester | 7-ketothiazolo[3,2-a]pyrimidine-5-carboxylic acid methyl ester | 7-oxo-5-thiazolo[3,2-a]pyrimidinecarboxylic acid methyl ester | MLS000075913 | SMR000013440 | cid_648108 | methyl 7-oxidanylidene-[1,3]thiazolo[3,2-a]pyrimidine-5-carboxylate | methyl 7-oxo-[1,3]thiazolo[3,2-a]pyrimidine-5-carboxylate
Type:
Small organic molecule
Emp. Form.:
C8H6N2O3S
Mol. Mass.:
210.21
SMILES:
COC(=O)c1cc(=O)nc2sccn12
Structure:
