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Target
Protein skinhead-1
Ligand
BDBM93778
Substrate
n/a
IC50
14300±n/a nM
Citation
 PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] 
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
  
Inhibitor
Name:
BDBM93778
Synonyms:
(2Z)-2-[(3-chloro-4-methyl-anilino)methylene]-4,4,4-trifluoro-1-(2-furyl)butane-1,3-dione | (2Z)-2-[(3-chloro-4-methylanilino)methylidene]-4,4,4-trifluoro-1-(2-furanyl)butane-1,3-dione | (2Z)-2-[(3-chloro-4-methylanilino)methylidene]-4,4,4-trifluoro-1-(furan-2-yl)butane-1,3-dione | (2Z)-2-[[(3-chloranyl-4-methyl-phenyl)amino]methylidene]-4,4,4-tris(fluoranyl)-1-(furan-2-yl)butane-1,3-dione | 2-{[(3-chloro-4-methylphenyl)amino]methylene}-4,4,4-trifluoro-1-(2-furyl)-1,3-butanedione | MLS000579302 | SMR000198583 | cid_2149945
Type:
Small organic molecule
Emp. Form.:
C16H11ClF3NO3
Mol. Mass.:
357.712
SMILES:
Cc1ccc(cc1Cl)N=CC(C(=O)c1ccco1)C(=O)C(F)(F)F |w:8.8|
Structure:
Search PDB for entries with ligand similarity: