Reaction Details
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Protein skinhead-1
Ligand
BDBM93847
Substrate
n/a
IC50
2780±n/a nM
Citation
PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
Inhibitor
Name:
BDBM93847
Synonyms:
MLS001018285 | N-(2-bromanyl-11H-pyrido[1,2-b][2,4]benzodiazepin-6-ylidene)-2,4-dinitro-benzamide | N-(2-bromo-11H-pyrido[1,2-b][2,4]benzodiazepin-6-ylidene)-2,4-dinitro-benzamide | N-(2-bromo-11H-pyrido[1,2-b][2,4]benzodiazepin-6-ylidene)-2,4-dinitrobenzamide | SMR000354560 | cid_2337552
Type:
Small organic molecule
Emp. Form.:
C20H12BrN5O5
Mol. Mass.:
482.244
SMILES:
[O-][N+](=O)c1ccc(C(=O)\N=C2/[N-]c3ccc(Br)c[n+]3Cc3ccccc23)c(c1)[N+]([O-])=O
Structure:
