Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93866
Substrate
n/a
IC50
44420±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93866
Synonyms:
2-chloranyl-4-[4-(4-chlorophenyl)piperazin-1-yl]pyrimidine | 2-chloro-4-[4-(4-chlorophenyl)-1-piperazinyl]pyrimidine | 2-chloro-4-[4-(4-chlorophenyl)piperazin-1-yl]pyrimidine | 2-chloro-4-[4-(4-chlorophenyl)piperazino]pyrimidine | MLS001178632 | SMR000476419 | cid_1713612
Type:
Small organic molecule
Emp. Form.:
C14H14Cl2N4
Mol. Mass.:
309.194
SMILES:
Clc1ccc(cc1)N1CCN(CC1)c1ccnc(Cl)n1
Structure:
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