Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93752
Substrate
n/a
IC50
30600±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93752
Synonyms:
2-(2-furanyl)-5-[(4-methylphenyl)methylthio]-1,3,4-oxadiazole | 2-(2-furyl)-5-[(4-methylbenzyl)sulfanyl]-1,3,4-oxadiazole | 2-(2-furyl)-5-[(4-methylbenzyl)thio]-1,3,4-oxadiazole | 2-(furan-2-yl)-5-[(4-methylphenyl)methylsulfanyl]-1,3,4-oxadiazole | MLS000540978 | SMR000126036 | cid_1479924
Type:
Small organic molecule
Emp. Form.:
C14H12N2O2S
Mol. Mass.:
272.322
SMILES:
Cc1ccc(CSc2nnc(o2)-c2ccco2)cc1
Structure:
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