Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM49288
Substrate
n/a
IC50
23110±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM49288
Synonyms:
(5-chloro-2-pyridyl)-[4-(2-thienyl)thiazol-2-yl]amine | 5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyridinamine | MLS000064746 | N-(5-chloranylpyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine | N-(5-chloro-2-pyridinyl)-4-thiophen-2-yl-2-thiazolamine | N-(5-chloropyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine | SMR000077573 | cid_2214576
Type:
Small organic molecule
Emp. Form.:
C12H8ClN3S2
Mol. Mass.:
293.795
SMILES:
Clc1ccc(Nc2nc(cs2)-c2cccs2)nc1
Structure:
Search PDB for entries with ligand similarity: