Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93788
Substrate
n/a
IC50
45530±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93788
Synonyms:
(E)-N-(4-Morpholin-4-ylmethyl-phenyl)-3-phenyl-acrylamide | (E)-N-[4-(4-morpholinylmethyl)phenyl]-3-phenyl-2-propenamide | (E)-N-[4-(morpholin-4-ylmethyl)phenyl]-3-phenyl-prop-2-enamide | (E)-N-[4-(morpholin-4-ylmethyl)phenyl]-3-phenylprop-2-enamide | (E)-N-[4-(morpholinomethyl)phenyl]-3-phenyl-acrylamide | MLS000591819 | SMR000218802 | cid_950916
Type:
Small organic molecule
Emp. Form.:
C20H22N2O2
Mol. Mass.:
322.4009
SMILES:
O=C(Nc1ccc(CN2CCOCC2)cc1)\C=C\c1ccccc1
Structure:
Search PDB for entries with ligand similarity: