Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93820
Substrate
n/a
IC50
13600±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93820
Synonyms:
(5-methyl-2-pyridyl)-[4-(2-thienyl)thiazol-2-yl]amine | 5-methyl-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyridinamine | MLS000664981 | N-(5-methyl-2-pyridinyl)-4-thiophen-2-yl-2-thiazolamine | N-(5-methylpyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine | SMR000294674 | cid_972421
Type:
Small organic molecule
Emp. Form.:
C13H11N3S2
Mol. Mass.:
273.377
SMILES:
Cc1ccc(Nc2nc(cs2)-c2cccs2)nc1
Structure:
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