Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93776
Substrate
n/a
IC50
42710±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93776
Synonyms:
MLS000580501 | N-[[3-chloranyl-4-[(4-fluorophenyl)methoxy]-5-methoxy-phenyl]methyl]cyclopentanamine;hydrochloride | N-[[3-chloro-4-[(4-fluorophenyl)methoxy]-5-methoxyphenyl]methyl]cyclopentanamine;hydrochloride | N-{3-chloro-4-[(4-fluorobenzyl)oxy]-5-methoxybenzyl}cyclopentanamine hydrochloride | SMR000199388 | [3-chloro-4-(4-fluorobenzyl)oxy-5-methoxy-benzyl]-cyclopentyl-amine;hydrochloride | cid_2950356
Type:
Small organic molecule
Emp. Form.:
C20H23ClFNO2
Mol. Mass.:
363.854
SMILES:
COc1cc(CNC2CCCC2)cc(Cl)c1OCc1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: