Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93840
Substrate
n/a
IC50
52770±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93840
Synonyms:
3-phenyl-5-(phenylsulfanylmethyl)-1,2-oxazole | 3-phenyl-5-[(phenylsulfanyl)methyl]isoxazole | 3-phenyl-5-[(phenylthio)methyl]isoxazole | MLS000721014 | SMR000335569 | cid_1479588
Type:
Small organic molecule
Emp. Form.:
C16H13NOS
Mol. Mass.:
267.346
SMILES:
C(Sc1ccccc1)c1cc(no1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: