Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM43693
Substrate
n/a
IC50
47930±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM43693
Synonyms:
(2Z)-2-[(4-bromoanilino)methylene]-4,4,4-trifluoro-1-(2-furyl)butane-1,3-dione | (2Z)-2-[(4-bromoanilino)methylidene]-4,4,4-trifluoro-1-(2-furanyl)butane-1,3-dione | (2Z)-2-[(4-bromoanilino)methylidene]-4,4,4-trifluoro-1-(furan-2-yl)butane-1,3-dione | (2Z)-2-[[(4-bromophenyl)amino]methylidene]-4,4,4-tris(fluoranyl)-1-(furan-2-yl)butane-1,3-dione | 2-{[(4-bromophenyl)amino]methylene}-4,4,4-trifluoro-1-(2-furyl)-1,3-butanedione | MLS000579283 | SMR000198563 | cid_2149933
Type:
Small organic molecule
Emp. Form.:
C15H9BrF3NO3
Mol. Mass.:
388.136
SMILES:
FC(F)(F)C(=O)C(C=Nc1ccc(Br)cc1)C(=O)c1ccco1 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: