Reaction Details
Report a problem with these data
Report a problem with these dataTarget
Heat shock protein hsp-16.2
Ligand
BDBM66482
Substrate
n/a
IC50
>64000±n/a nM
Citation
PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
Inhibitor
Name:
BDBM66482
Synonyms:
(E)-3-(4-bromophenyl)-1-[4-(5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenyl]-2-propen-1-one | (E)-3-(4-bromophenyl)-1-[4-(5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenyl]prop-2-en-1-one | MLS000391412 | SMR000260448 | cid_6014681
Type:
Small organic molecule
Emp. Form.:
C19H17BrN2OS
Mol. Mass.:
401.32
SMILES:
Brc1ccc(C=CC(=O)c2ccc(cc2)N=C2NCCCS2)cc1 |w:15.15,6.6|
Structure:
