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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90034
Substrate
n/a
IC50
3570±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90034
Synonyms:
4-(2-furanylmethylamino)-3-nitrobenzamide | 4-(2-furfurylamino)-3-nitro-benzamide | 4-(furan-2-ylmethylamino)-3-nitro-benzamide | 4-(furan-2-ylmethylamino)-3-nitrobenzamide | 4-[(2-furylmethyl)amino]-3-nitrobenzamide | MLS000574229 | SMR000195820 | cid_2907140
Type:
Small organic molecule
Emp. Form.:
C12H11N3O4
Mol. Mass.:
261.2334
SMILES:
NC(=O)c1ccc(NCc2ccco2)c(c1)[N+]([O-])=O
Structure:
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