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Target
Perilipin-5
Ligand
BDBM94574
Substrate
n/a
IC50
1913±n/a nM
Citation
 PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) PubChem Bioassay (2012)[AID] 
Target
Name:
Perilipin-5
Synonyms:
LSDP5 | OXPAT | PAT-1 | PLIN5 | PLIN5_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50774.20
Organism:
Homo sapiens (Human)
Description:
gi_116292172
Residue:
463
Sequence:
MSEEEAAQIPRSSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETVVTSAKDVVASSVTGVVDLARRGRRWSVELKRSVSHAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQRPPESRRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVERPEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMGVAGDICEQEPETPSCPVKHTLMPELDF
  
Inhibitor
Name:
BDBM94574
Synonyms:
MLS002699028 | SMR001563150 | [(1R,2S,4E,8Z,12S,13S)-12-hydroxy-4,8,12-trimethyl-16-methylidene-15-oxo-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] acetate | [(1R,2S,4E,8Z,12S,13S)-4,8,12-trimethyl-16-methylidene-12-oxidanyl-15-oxidanylidene-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] ethanoate | acetic acid [(1R,2S,4E,8Z,12S,13S)-12-hydroxy-15-keto-4,8,12-trimethyl-16-methylene-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] ester | acetic acid [(1R,2S,4E,8Z,12S,13S)-12-hydroxy-4,8,12-trimethyl-16-methylene-15-oxo-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] ester | cid_44825950
Type:
Small organic molecule
Emp. Form.:
C22H32O5
Mol. Mass.:
376.4865
SMILES:
CC(=O)O[C@H]1C\C(C)=C\CC\C(C)=C/CC[C@](C)(O)[C@@H]2C[C@@H]1C(=C)C(=O)O2 |c:12,t:7|
Structure:
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