Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94903
Substrate
n/a
IC50
18100±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94903
Synonyms:
MLS000769087 | N-(2-oxolanylmethyl)-2-(4-propan-2-yloxyphenyl)-4-quinazolinamine | N-(oxolan-2-ylmethyl)-2-(4-propan-2-yloxyphenyl)quinazolin-4-amine | SMR000433802 | [2-(4-Isopropoxy-phenyl)-quinazolin-4-yl]-(tetrahydro-furan-2-ylmethyl)-amine | [2-(4-isopropoxyphenyl)quinazolin-4-yl]-(tetrahydrofurfuryl)amine | cid_3540331
Type:
Small organic molecule
Emp. Form.:
C22H25N3O2
Mol. Mass.:
363.4528
SMILES:
CC(C)Oc1ccc(cc1)-c1nc(NCC2CCCO2)c2ccccc2n1
Structure:
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