Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM95056
Substrate
n/a
IC50
>80000±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM95056
Synonyms:
2-(2-furanyl)-5-phenyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | 2-(2-furyl)-5-phenyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | 2-(2-furyl)-5-phenyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one | 2-(furan-2-yl)-5-phenyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | MLS000066245 | SMR000079892 | cid_1266395
Type:
Small organic molecule
Emp. Form.:
C15H10N4O2
Mol. Mass.:
278.2655
SMILES:
O=c1cc(nc2nc([nH]n12)-c1ccco1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: