Reaction Details
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Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM95185
Substrate
n/a
IC50
25000±n/a nM
Citation
PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
Inhibitor
Name:
BDBM95185
Synonyms:
2-[[6-[(2-carbethoxyphenyl)carbamoyl]-1,2,3,4-tetrahydroacridin-9-yl]thio]acetic acid | 2-[[6-[(2-ethoxycarbonylanilino)-oxomethyl]-1,2,3,4-tetrahydroacridin-9-yl]thio]acetic acid | 2-[[6-[(2-ethoxycarbonylphenyl)carbamoyl]-1,2,3,4-tetrahydroacridin-9-yl]sulfanyl]acetic acid | 2-[[6-[(2-ethoxycarbonylphenyl)carbamoyl]-1,2,3,4-tetrahydroacridin-9-yl]sulfanyl]ethanoic acid | MLS000924774 | SMR000623657 | cid_24789603
Type:
Small organic molecule
Emp. Form.:
C25H24N2O5S
Mol. Mass.:
464.533
SMILES:
CCOC(=O)c1ccccc1NC(=O)c1ccc2c(SCC(O)=O)c3CCCCc3nc2c1
Structure:
