Reaction Details Report a problem with these data
Target
High affinity choline transporter 1
Ligand
BDBM95194
Substrate
n/a
IC50
3850±n/a nM
Citation
 PubChem, PC Dose responses of compounds that inhibit the Choline Transporter (CHT) in a 3H-choline uptake radioactive assay PubChem Bioassay (2012)[AID] 
Target
Name:
High affinity choline transporter 1
Synonyms:
CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1
Type:
PROTEIN
Mol. Mass.:
63194.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1464247
Residue:
580
Sequence:
MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFKTLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM95194
Synonyms:
2-chloranyl-4-nitro-N-[4-(pyridin-2-ylsulfamoyl)phenyl]benzamide;2,2,2-tris(fluoranyl)ethanoic acid | 2-chloro-4-nitro-N-[4-(2-pyridinylsulfamoyl)phenyl]benzamide;2,2,2-trifluoroacetic acid | 2-chloro-4-nitro-N-[4-(2-pyridylsulfamoyl)phenyl]benzamide;2,2,2-trifluoroacetic acid | 2-chloro-4-nitro-N-[4-(pyridin-2-ylsulfamoyl)phenyl]benzamide;2,2,2-trifluoroacetic acid | VU0464767-1 | cid_54759172
Type:
Small organic molecule
Emp. Form.:
C18H13ClN4O5S
Mol. Mass.:
432.838
SMILES:
[O-][N+](=O)c1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccccn2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: