Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95383
Substrate
n/a
IC50
125299±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM95383
Synonyms:
3-nitro-4-(1-phenylethylamino)-1-benzopyran-2-one | 3-nitro-4-(1-phenylethylamino)chromen-2-one | 3-nitro-4-(1-phenylethylamino)coumarin | 3-nitro-4-[(1-phenylethyl)amino]-2H-chromen-2-one | MLS000727618 | SMR000306315 | cid_16187873
Type:
Small organic molecule
Emp. Form.:
C17H14N2O4
Mol. Mass.:
310.3041
SMILES:
CC(Nc1c([N+]([O-])=O)c(=O)oc2ccccc12)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: