Reaction Details
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Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM63836
Substrate
n/a
IC50
>51724±n/a nM
Citation
PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
Inhibitor
Name:
BDBM63836
Synonyms:
Isonicotinic acid [(E)-3-benzo[1,3]dioxol-5-yl-1-methyl-prop-2-en-(Z)-ylidene]-hydrazide | MLS000768521 | N-[(Z)-[(E)-3-(1,3-benzodioxol-5-yl)-1-methyl-prop-2-enylidene]amino]isonicotinamide | N-[[(E)-3-(1,3-benzodioxol-5-yl)-1-methyl-prop-2-enylidene]amino]isonicotinamide | N-[[(E)-4-(1,3-benzodioxol-5-yl)but-3-en-2-ylidene]amino]-4-pyridinecarboxamide | N-[[(E)-4-(1,3-benzodioxol-5-yl)but-3-en-2-ylidene]amino]pyridine-4-carboxamide | SMR000431854 | cid_871065
Type:
Small organic molecule
Emp. Form.:
C17H15N3O3
Mol. Mass.:
309.3193
SMILES:
CC(C=Cc1ccc2OCOc2c1)=NNC(=O)c1ccncc1 |w:13.15,3.3|
Structure:
