Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94946
Substrate
n/a
IC50
33000±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94946
Synonyms:
2-(2-fluorophenyl)-N-(3-morpholin-4-ylpropyl)quinazolin-4-amine | 2-(2-fluorophenyl)-N-[3-(4-morpholinyl)propyl]-4-quinazolinamine | MLS000036511 | SMR000037729 | [2-(2-fluorophenyl)quinazolin-4-yl]-(3-morpholinopropyl)amine | cid_661646
Type:
Small organic molecule
Emp. Form.:
C21H23FN4O
Mol. Mass.:
366.4319
SMILES:
Fc1ccccc1-c1nc(NCCCN2CCOCC2)c2ccccc2n1
Structure:
Search PDB for entries with ligand similarity: