Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94892
Substrate
n/a
IC50
24200±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94892
Synonyms:
5-(3-azido-4-chloranyl-phenyl)-6-ethyl-pyrimidine-2,4-diamine;ethanesulfonic acid | 5-(3-azido-4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine;ethanesulfonic acid | CHEMBL299045 | MLS002701720 | SMR001565317 | [2-amino-5-(3-azido-4-chloro-phenyl)-6-ethyl-pyrimidin-4-yl]amine;esylic acid | cid_343097 | cid_343098
Type:
Small organic molecule
Emp. Form.:
C12H12ClN7
Mol. Mass.:
289.724
SMILES:
CCc1nc(N)nc(N)c1-c1ccc(Cl)c(c1)N=[N+]=[N-]
Structure:
Search PDB for entries with ligand similarity: