Reaction Details Report a problem with these data
Target
RecBCD enzyme subunit RecD
Ligand
BDBM93629
Substrate
n/a
IC50
62468±n/a nM
Citation
 PubChem, PC Absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay (2013)[AID] 
Target
Name:
RecBCD enzyme subunit RecD
Synonyms:
RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
66906.68
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130723
Residue:
608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE
  
Inhibitor
Name:
BDBM93629
Synonyms:
Isonicotinic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide | MLS000768056 | N-[(E)-(5-nitro-2-furanyl)methylideneamino]-4-pyridinecarboxamide | N-[(E)-(5-nitro-2-furyl)methyleneamino]isonicotinamide | N-[(E)-(5-nitrofuran-2-yl)methylideneamino]pyridine-4-carboxamide | SMR000431365 | cid_5469569
Type:
Small organic molecule
Emp. Form.:
C11H8N4O4
Mol. Mass.:
260.2056
SMILES:
[O-][N+](=O)c1ccc(\C=N\NC(=O)c2ccncc2)o1
Structure:
Search PDB for entries with ligand similarity: