Reaction Details
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Report a problem with these dataTarget
T cell receptor alpha variable 4
Ligand
BDBM96330
Substrate
n/a
IC50
>94057±n/a nM
Citation
PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
Inhibitor
Name:
BDBM96330
Synonyms:
MLS000714751 | N-[(salicyloylamino)thiocarbamoyl]nicotinamide | N-[[(2-hydroxybenzoyl)amino]carbamothioyl]pyridine-3-carboxamide | N-[[(2-hydroxyphenyl)carbonylamino]carbamothioyl]pyridine-3-carboxamide | N-[[[(2-hydroxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-3-pyridinecarboxamide | SMR000274730 | cid_1933112
Type:
Small organic molecule
Emp. Form.:
C14H12N4O3S
Mol. Mass.:
316.335
SMILES:
Oc1ccccc1C(=O)NNC(=S)NC(=O)c1cccnc1
Structure:
