Reaction Details Report a problem with these data
Target
T cell receptor alpha variable 4
Ligand
BDBM50056891
Substrate
n/a
IC50
>93941±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] 
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
  
Inhibitor
Name:
BDBM50056891
Synonyms:
2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydrazide | 2-hydroxybenzoic acid 2-(2-hydroxybenzoyl)hydrazide | CHEMBL36303 | cid_65303
Type:
Small organic molecule
Emp. Form.:
C14H12N2O4
Mol. Mass.:
272.2561
SMILES:
Oc1ccccc1C(=O)NNC(=O)c1ccccc1O
Structure:
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