Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96570
Substrate
n/a
EC50
>29904±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G protein alpha 16 | G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | Guanine nucleotide-binding protein subunit alpha-15 [Y147C]
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96570
Synonyms:
2-oxo-3-[(2-phenylethyl)amino]-2,5,6,7-tetrahydro-1H-azepine-4-carbonitrile | 7-keto-6-(phenethylamino)-1,2,3,4-tetrahydroazepine-5-carbonitrile | 7-oxidanylidene-6-(2-phenylethylamino)-1,2,3,4-tetrahydroazepine-5-carbonitrile | 7-oxo-6-(2-phenylethylamino)-1,2,3,4-tetrahydroazepine-5-carbonitrile | MLS000090103 | SMR000024721 | cid_3243145
Type:
Small organic molecule
Emp. Form.:
C15H17N3O
Mol. Mass.:
255.315
SMILES:
O=C1NCCCC(C#N)C1=NCCc1ccccc1 |w:10.11|
Structure:
Search PDB for entries with ligand similarity: