Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM49173
Substrate
n/a
IC50
443.79±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM49173
Synonyms:
(4-aminoquinazolin-2-yl)-phenyl-amine;hydrochloride | 2-N-phenylquinazoline-2,4-diamine;hydrochloride | MLS000026767 | N*2*-Phenyl-quinazoline-2,4-diamine | N2-phenylquinazoline-2,4-diamine;hydrochloride | SMR000014424 | cid_2952123
Type:
Small organic molecule
Emp. Form.:
C14H12N4
Mol. Mass.:
236.2719
SMILES:
Nc1nc(Nc2ccccc2)nc2ccccc12
Structure:
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