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Target
Trace amine-associated receptor 1
Ligand
BDBM96553
Substrate
n/a
IC50
1494±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96553
Synonyms:
3-(3-Phenyl-pyrrolidin-1-yl)-1-thiophen-2-yl-propan-1-one | 3-(3-phenyl-1-pyrrolidinyl)-1-thiophen-2-yl-1-propanone;hydrochloride | 3-(3-phenylpyrrolidin-1-yl)-1-thiophen-2-yl-propan-1-one;hydrochloride | 3-(3-phenylpyrrolidin-1-yl)-1-thiophen-2-ylpropan-1-one;hydrochloride | 3-(3-phenylpyrrolidino)-1-(2-thienyl)propan-1-one;hydrochloride | MLS000035953 | SMR000011654 | cid_2893244
Type:
Small organic molecule
Emp. Form.:
C17H19NOS
Mol. Mass.:
285.404
SMILES:
O=C(CCN1CCC(C1)c1ccccc1)c1cccs1
Structure:
Search PDB for entries with ligand similarity: