Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM49184
Substrate
n/a
IC50
1647±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM49184
Synonyms:
(4-aminoquinazolin-2-yl)-(3-fluorophenyl)amine;hydrochloride | 2-N-(3-fluorophenyl)quinazoline-2,4-diamine;hydrochloride | MLS000034907 | N*2*-(3-Fluoro-phenyl)-quinazoline-2,4-diamine | N2-(3-fluorophenyl)quinazoline-2,4-diamine;hydrochloride | SMR000014425 | cid_2952346
Type:
Small organic molecule
Emp. Form.:
C14H11FN4
Mol. Mass.:
254.2623
SMILES:
Nc1nc(Nc2cccc(F)c2)nc2ccccc12
Structure:
Search PDB for entries with ligand similarity: