Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96619
Substrate
n/a
IC50
6233±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96619
Synonyms:
4-{[(isobutyrylamino)carbothioyl]amino}-N-(4-methoxyphenyl)benzenesulfonamide | MLS000539757 | N-[[4-[(4-methoxyphenyl)sulfamoyl]anilino]-sulfanylidenemethyl]-2-methylpropanamide | N-[[4-[(4-methoxyphenyl)sulfamoyl]phenyl]carbamothioyl]-2-methyl-propanamide | N-[[4-[(4-methoxyphenyl)sulfamoyl]phenyl]carbamothioyl]-2-methylpropanamide | N-[[4-[(4-methoxyphenyl)sulfamoyl]phenyl]thiocarbamoyl]-2-methyl-propionamide | SMR000162376 | cid_1792532
Type:
Small organic molecule
Emp. Form.:
C18H21N3O4S2
Mol. Mass.:
407.507
SMILES:
COc1ccc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)C(C)C)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: